Salmonella-induced Psoas Abscess in a Patient with Multiple Myeloma: A Case Report and Systematic Literature Review
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CASE REPORT
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5 September 2025

Salmonella-induced Psoas Abscess in a Patient with Multiple Myeloma: A Case Report and Systematic Literature Review

Mediterr J Infect Microb Antimicrob. Published online 5 September 2025.
1. Sivas Cumhuriyet University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Sivas, Turkiye
2. Sivas Cumhuriyet University Faculty of Medicine, Department of Anesthesiology and Reanimation, Sivas, Turkiye
3. Sivas Cumhuriyet University Faculty of Medicine, Division of Hematology, Department of Internal Diseases, Sivas, Turkiye
No information available.
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E-Pub Date: 05.09.2025
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Abstract

Salmonella is a gram-negative enteric bacillus primarily responsible for gastrointestinal infections. Psoas abscess due to Salmonella is an exceptionally rare clinical entity. Here, we have presented the case of a 65-year-old woman with multiple myeloma who developed a Salmonella-induced psoas abscess. She was admitted to the emergency department with persistent nausea and vomiting for the past 1 month. Blood cultures grew Salmonella species, and abdominal computed tomography (CT) revealed a 43-mm abscess in the right psoas muscle. On the 10th day of hospitalization, CT-guided percutaneous drainage was performed, and Salmonella species was isolated from the abscess culture. Despite administering 6 weeks of antibiotic therapy, the patient’s clinical course was fatal. We also reviewed 29 previously published cases of Salmonella-associated psoas abscesses, among which two (6.8%) had fatal outcomes. This case adds to the limited literature by highlighting a rare clinical presentation and providing a review of the clinical features, therapeutic strategies, and outcomes of Salmonella-related psoas abscesses.

Keywords:
Salmonella, psoas abscess, immunosuppression, multiple myeloma, antibiotic resistance