Papillotrema (Cryptococcus) laurentii Giderek Artan Bir Sorun mu Oluyor? Üçüncü Basamak Bir Hastanede Olgu Serisi Eşliğinde Literatür Derlemesi
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Papillotrema (Cryptococcus) laurentii Giderek Artan Bir Sorun mu Oluyor? Üçüncü Basamak Bir Hastanede Olgu Serisi Eşliğinde Literatür Derlemesi

Mediterr J Infect Microb Antimicrob 2025;14:8-8 DOI: 10.4274/mjima.galenos.2025.24316.8
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İzin

Öz

Giriş

Kriptokokozis, özellikle immün sistemi baskılanmış hastalarda görülen önemli bir fırsatçı mantar enfeksiyonudur. Papillotrema laurentii son yıllarda özellikle immün sistemi baskılanmış hastalarda bildirilmiştir. Bu makalede literatür derlemesi yapılarak Papillotrema laurentii ile ilişkili enfeksiyonların veya kolonizasyonların tanı ve tedavisine rehberlik etmek amaçlanmıştır.

Gereç ve Yöntem

Çalışmamıza, 2017-2022 yılları arasında herhangi bir kültür örneğinde Papillotrema laurentii izolasyonu saptanan hastalar dahil edilmiştir. Literatür taramaları, Scopus, Web of Science, MEDLINE (PubMed) ve Google Scholar gibi elektronik veri tabanlarında gerçekleştirilmiştir.

Bulgular

Son beş yıl içerisinde hastanemizde kültür örneklerinde Papillotrema laurentii izole edilen dokuz hasta tespit edilmiştir. Yapılan literatür taramasında, 1998-2022 yılları arasında Papillotrema laurentii enfeksiyonu gelişen toplam kırk olguyu içeren otuz beş yayın bulunmuştur. Geniş spektrumlu antibiyotik kullanımı ile invaziv araç veya kateter varlığı en sık karşılaşılan risk faktörleri olarak belirlenmiştir.

Sonuç

Nadir bir etken olarak bildirilen Papillotrema laurentii, birçok sistemi tutarak çeşitli enfeksiyonlara yol açabilmektedir. Bu nedenle, özellikle geniş spektrumlu antibiyotik ve steroid tedavisi kullanan hastalarda, bu tür nadir etkenlerin enfeksiyon etkeni olarak karşımıza çıkabileceği akılda tutulmalıdır.

Anahtar Kelimeler: Papiliotrema laurentii, mantar hastalıkları, Kriptokokkoz

Kaynakça

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